Robert D. Lovchik, Fabio Bianco, et al.
Analytical Chemistry
Lab-on-a-chip (LOC) devices are broadly used for research in the life sciences and diagnostics and represent a very fast moving field. LOC devices are designed, prototyped and assembled using numerous strategies and materials but some fundamental trends are that these devices typically need to be (1) sealed, (2) supplied with liquids, reagents and samples, and (3) often interconnected with electrical or microelectronic components. In general, closing and connecting to the outside world these miniature labs remain a challenge irrespectively of the type of application pursued. Here, we review methods for sealing and connecting LOC devices using standard approaches as well as recent state-of-the-art methods. This review provides easy-to-understand examples and targets the microtechnology/engineering community as well as researchers in the life sciences.
Robert D. Lovchik, Fabio Bianco, et al.
Analytical Chemistry
Vesna Bacheva, Federico Paratore, et al.
MicroTAS 2019
Linda K. Sundberg, Gregory M. Wallraff, et al.
Proceedings of SPIE - The International Society for Optical Engineering 2010
Jaione Tirapu-Azpiroz, Yuksel Temiz, et al.
Biomedical Microdevices