Compression for data archiving and backup revisited
Corneliu Constantinescu
SPIE Optical Engineering + Applications 2009
We have performed ultrahigh vacuum (UHV) scanning tunneling microscopy studies of biological molecules by developing a UHV compatible cell wherein a drop of ultrapure water containing nanograms of molecules is evaporated from a strongly chemisorbing Pt(111) surface in an Ar ambient. Images are presented for hydroquinone; oligomers including pentaphenyl ether, enkephalin, and sodium dodecyl sulfate; large homopolymers of lysine and glycine; the proteins calmodulin, tropomyosin, and immunoglobin G; and double- and single-stranded plasmid DNA. In all cases the apparent height is only a few Å. Imaging properties understandably vary from clearly resolved internal molecular structure for hydroquinone to diffuse, artifact-prone images for molecules which exceed tens of angstroms in thickness. These data do not support claims for atomic resolution imaging of complex biomolecules. © 1993, American Chemical Society. All rights reserved.
Corneliu Constantinescu
SPIE Optical Engineering + Applications 2009
A. Krol, C.J. Sher, et al.
Surface Science
R.J. Gambino, N.R. Stemple, et al.
Journal of Physics and Chemistry of Solids
Michael Ray, Yves C. Martin
Proceedings of SPIE - The International Society for Optical Engineering